Premium
Increased risk of anxiety among patients with urolithiasis: A nationwide population‐based cohort study
Author(s) -
Lien ChiShun,
Huang ChiPing,
Chung ChiJung,
Lin ChengLi,
Chang ChaoHsiang
Publication year - 2015
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/iju.12865
Subject(s) - medicine , hazard ratio , anxiety , confidence interval , cohort , depression (economics) , incidence (geometry) , cohort study , rate ratio , population , psychiatry , environmental health , economics , physics , optics , macroeconomics
Objectives To investigate whether patients with urolithiasis are at an increased risk of anxiety and depression. Methods We used universal insurance claims data in Taiwan from 2000 to 2011 to identify patients with newly diagnosed urolithiasis ( n = 32 617) and those without urolithiasis ( n = 130 465). Incidences, hazard ratios, and incidence rate ratios of anxiety and depression were determined in both cohorts in terms of baseline demographic characteristics and comorbidities until December 2011. Results The urolithiasis cohort yielded a higher incidence of anxiety (11.9 vs 6.91 per 1000 person‐years) with an adjusted hazard ratio of 1.5 (95% confidence interval 1.42–1.57) than the non‐urolithiasis cohort. The urolithiasis cohort also showed a higher incidence of depression (5.79 vs 3.95 per 1000 person‐years) with an adjusted hazard ratio of 1.26 (95% confidence interval 1.18–1.35) than the non‐urolithiasis cohort. Regardless of the patients' baseline comorbidities, patients with urolithiasis showed a higher incidence rate ratio of anxiety and depression than those without urolithiasis (with no comorbidities: adjusted hazard ratio 1.62, 95% confidence interval 1.49–1.76] for anxiety and adjusted hazard ratio 1.37, 95% confidence interval 1.23–1.54 for depression). Conclusion Urolithiasis is recurrent, and significantly associated with anxiety and depression. Therefore, urologists should diagnose patients suspected with this disease and provide proper medical care.