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Health‐related quality of life after radical cystectomy and neobladder reconstruction in women: Impact of voiding and continence status
Author(s) -
Zahran Mohamed H,
ElHefnawy Ahmed S,
Zidan Essam M,
ElBilsha Mona A,
Taha DiaaEldin,
AliElDein Bedeir
Publication year - 2014
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/iju.12452
Subject(s) - medicine , cystectomy , quality of life (healthcare) , urology , urinary continence , gynecology , bladder cancer , nursing , prostatectomy , prostate cancer , cancer
Objectives To assess health‐related quality of life, and the impact of night‐time incontinence and chronic urinary retention on health‐related quality of life in women with bladder cancer after radical cystectomy and orthotopic neobladder. Methods The study included 74 women who underwent radical cystectomy and orthotopic neobladder, and completed 1 year of follow up. Health‐related quality of life was evaluated using the questionnaires of the E uropean O rganization for R esearch and T reatment of C ancer‐ Q uality of L ife Questionnaire and the F unctional A ssessment of C ancer T herapy bladder cancer‐specific form. Health‐related quality of life was compared with an age‐matched control group. The impact of night‐time incontinence and chronic urinary retention on health‐related quality of life was assessed. Results The study group included 18 completely continent patients with spontaneous voiding, 29 with night‐time incontinence and 27 with chronic urinary retention. The study group was statistically significantly lower in all domains of health‐related quality of life than the control group. In all domains of the E uropean O rganization for R esearch and T reatment of C ancer‐Quality of Life Questionnaire and F unctional A ssessment of C ancer T herapy bladder cancer‐specific form, completely continent women were comparable with those with chronic urinary retention. Women with night‐time incontinence had a significantly worse health‐related quality of life than completely continent women, shown by the mean global health score ( P = 0.038), social functioning score ( P = 0.012), pain E uropean O rganization for R esearch and T reatment of C ancer‐Quality of Life Questionnaire score ( P = 0.04), and functional well‐being F unctional A ssessment of C ancer T herapy bladder cancer‐specific form ( P = 0.049) score. Conclusions After radical cystectomy and orthotopic neobladder in women, health‐related quality of life is lower than that of the normal population. Night‐time incontinence has a negative impact on social life and most domains of health‐related quality of life. Thus, night‐time incontinence has a higher social impact than chronic urinary retention.