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Urinary incontinence in patients with A lzheimer's disease: Relationship between symptom status and urodynamic diagnoses
Author(s) -
Lee Seong Ho,
Cho Sung Tae,
Na Hae Ri,
Ko Seok Bum,
Park Moon Ho
Publication year - 2014
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/iju.12420
Subject(s) - medicine , urinary incontinence , rating scale , dementia , urinary system , urology , disease , physical therapy , psychology , developmental psychology
Objective To assess factors associated with detrusor overactivity in urinary incontinence patients with A lzheimer's disease, and to determine the correlation between the degree of A lzheimer's disease and the presence of detrusor overactivity. Methods A total of 144 A lzheimer's disease patients (48 men, 96 women; aged 56–97 years) with urinary incontinence were enrolled in this protocol. Cognitive testing was carried out using the Mini‐Mental State Examination, the Clinical Dementia Rating scale, the Global Deterioration Scale and B arthel's Activities of Daily Living. Urinary incontinence was assessed using a frequency–volume chart and the Incontinence Questionnaire on Urinary Incontinence Short Form. All study participants had a urodynamic study carried out. Results Based on the Incontinence Questionnaire on Urinary Incontinence Short Form, the most common type of urinary incontinence was urge urinary incontinence followed by enuresis in men, whereas women most commonly complained of urge urinary incontinence followed by stress urinary incontinence. Detrusor overactivity was found in 57.6% of patients (25 men, 58 women) on urodynamic study. No statistical differences were found between those with and without detrusor overactivity in terms of age, sex or duration of education. No significant correlation was found between changes in Incontinence Questionnaire on Urinary Incontinence Short Form scores and those in the Mini‐Mental State Examination, Clinical Dementia Rating and B arthel's Activities of Daily Living status. Multiple logistic regression analysis showed the presence of detrusor overactivity could be predicted using Clinical Dementia Rating and B arthel's Activities of Daily Living scores ( P < 0.05). Conclusions The most common type of urinary incontinence in patients with A lzheimer's disease is urge urinary incontinence. Clinical Dementia Rating and B arthel's Activities of Daily Living predict the severity of detrusor overactivity in this patient population.