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Defining and identifying predictors of rapid response to pediatric obesity treatment
Author(s) -
Eichen Dawn M.,
Mestre Zoe L.,
Strong David R.,
Rhee Kyung E.,
Boutelle Kerri N.
Publication year - 2020
Publication title -
pediatric obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.226
H-Index - 69
eISSN - 2047-6310
pISSN - 2047-6302
DOI - 10.1111/ijpo.12621
Subject(s) - medicine , weight loss , overweight , percentile , obesity , body mass index , pediatrics , weight change , statistics , mathematics
Summary Early weight loss (rapid response [RR]) is associated with better outcomes in adults. Less is known about RR in children enrolled in weight‐loss treatment. The aim of the current study was to establish an RR weight‐loss threshold following 4 weeks of pediatric obesity treatment and identify characteristics associated with achieving RR. One hundred thirty‐seven children aged 8 to 12 with overweight/obesity and parents participated in 6 months of family‐based or parent‐based treatment. Receiver operating characteristic curves evaluated how weight loss at week 4 related to decreases of 5% at posttreatment and 10% at 6‐ and 18‐month follow‐ups of standardized body mass index (BMIz), percentage distance of a child's BMI from the median BMI for sex and age, and percentage above the 95th percentile. Weight loss of 2.4% to 3.4% at week 4 predicted 5% change at posttreatment (AUC's = .68‐.75; P 's ≤ .002) and 10% change at 6‐month follow‐up (AUC's = .63‐.70; P 's ≤ .02). No model was significant at 18‐month follow‐up. Amount of parent weight (lbs) change at week 4 was associated with child achieving RR. Males and Non‐Hispanic Whites were more likely to achieve RR. This threshold could be used to mark early significant progress and guide clinical evaluations of treatment response to paediatric obesity treatment.