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Correlation of hematological parameters and cycle threshold in ambulatory patients with SARS‐CoV‐2 infection
Author(s) -
GirónPérez Daniel Alberto,
BenitezTrinidad Alma Betsaida,
RuizManzano Rocio Alejandra,
ToledoIbarra Gladys Alejandra,
VenturaRamón Guadalupe Herminia,
CovantesRosales Carlos Eduardo,
OjedaDurán Ansonny Jhovany,
DíazReséndiz Karina Janice Guadalupe,
MercadoSalgado Ulises,
GirónPérez Manuel Iván
Publication year - 2021
Publication title -
international journal of laboratory hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.705
H-Index - 55
eISSN - 1751-553X
pISSN - 1751-5521
DOI - 10.1111/ijlh.13606
Subject(s) - medicine , mean corpuscular volume , mean corpuscular hemoglobin concentration , anosmia , hematocrit , hemoglobin , obesity , mean corpuscular hemoglobin , correlation , immunology , gastroenterology , covid-19 , disease , geometry , mathematics , infectious disease (medical specialty)
Former studies have shown that hematologic parameters are affected by the SARS‐CoV‐2 infection which has caused a global health problem. Therefore, this research aims to identify the most frequent symptoms and comorbidities in SARS‐CoV‐2 infected outpatients; besides, to analyze hematological parameters and their correlation with cycle threshold (Ct) values. Methods We analyzed a total of sixty outpatients with SARS‐CoV‐2 infection. They were divided according to sex. Afterward, a questionnaire was carried out to find out their symptoms and comorbidities. Additionally, blood biometry data were correlated with the Ct value, respectively. Results Sixty patients were analyzed; the mean age was 43 years. All patients were from Nayarit, Mexico. The frequency index showed that the main symptoms were headache and anosmia, and the comorbidities were obesity and smoking. The analysis of blood biometry showed a clear increase in red blood cells (RBC) related parameters in women. In both sexes an increase in the number of white blood cells (WBC) was observed. Also, all the hematological alterations correlated with the grade of infection. Conclusion Headache and anosmia are the most common symptoms according to the frequency index, the main comorbidities were obesity and smoking. Also, there is a Ct value correlation with hematological parameters (WBC, mean corpuscular volume, mean corpuscular hemoglobin, hemoglobin); they can be used as a prognostic marker of infection.