z-logo
Premium
Evaluation of Mindray BC ‐5000 hematology analyzer: a new miniature 5‐part WBC differential instrument
Author(s) -
Xiang D.,
Yue J.,
Lan Y.,
Sha C.,
Ren S.,
Li Y.,
Li M.,
Wang C.
Publication year - 2015
Publication title -
international journal of laboratory hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.705
H-Index - 55
eISSN - 1751-553X
pISSN - 1751-5521
DOI - 10.1111/ijlh.12370
Subject(s) - hematology analyzer , basophil , white blood cell , spectrum analyzer , hematology , reproducibility , medicine , blood cell , cell counting , eosinophil , platelet , pathology , biomedical engineering , chemistry , immunology , chromatography , computer science , telecommunications , immunoglobulin e , asthma , antibody , cancer , cell cycle
Summary Introduction The Mindray BC ‐5000 automated hematology analyzer is a miniature, automated hematology analyzer, and 5‐part leukocyte differential counter for in vitro diagnostic use in clinical laboratories. Methods Precision, linearity, carryover, and method comparison were carried out. The analyzer was evaluated and compared with the Sysmex XE ‐2100 hematology analyzer and manual microscopic in the hematology laboratory of a tertiary hospital in Chinese. Results There were minimal carryover (<0.25%), and excellent linearity for white blood cell, and platelet counts ( r  > 0.99). Within‐run precision was good at all levels for the routine cell blood count parameters ( CV  < 3.5%). Between‐run precision was acceptable at all levels for the analysis parameters ( CV  < 5%) except for eosinophil and basophil ( CV % >10%). BC ‐5000 displayed very good correlation ( r  > 0.94) with the XE ‐2100 for cell blood count and cell differential parameters except for basophil ( r  = 0.72). The comparison of 258 leukocyte differential count results analyzed in parallel with manual microscopy, BC ‐5000 analyzer showed perfect specificity (93%) and negative predictive value (90%) on abnormal blood samples. Conclusion It is concluded that the overall performance of the BC ‐5000 is acceptable. The miniature analyzer is suitable for use in small‐ to medium‐size laboratories.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here