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Evaluation of the Microsemi CRP , an automated hematology analyzer for rapid 3‐part WBC differential and CRP using whole blood
Author(s) -
Nomura N.,
Saito K.,
Ikeda M.,
Yuasa S.,
Pastore M.,
Chabert C.,
Kono E.,
Sakai A.,
Tanaka H.,
Ikemoto T.,
Takubo T.
Publication year - 2015
Publication title -
international journal of laboratory hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.705
H-Index - 55
eISSN - 1751-553X
pISSN - 1751-5521
DOI - 10.1111/ijlh.12312
Subject(s) - hematology analyzer , repeatability , medicine , reproducibility , correlation coefficient , spectrum analyzer , whole blood , c reactive protein , point of care , point of care testing , gastroenterology , immunology , pathology , chromatography , chemistry , mathematics , statistics , electrical engineering , engineering , inflammation
Summary Introduction We evaluated the basic performance of Microsemi CRP , an unique automated hematology analyzer which can simultaneously measure CBC including 3‐part WBC differential (3‐Diff) and CRP using whole blood treated with EDTA ‐2K anticoagulant. Method We found that it produced generally the acceptable results for all parameters performed (repeatability, reproducibility, linearity, interference effect, carry over, and correlation) using control materials, fresh human whole bloods, and serum samples. Results CBC data examined using Microsemi CRP showed the good correlation with the previous model, Micros CRP 200 ( r ≧ 0.9), and also those obtained using the routine analyzer, ADVIA 2120i ( r ≧ 0.989). Concerning the 3‐Diff, both GRA (%) and LYM (%) showed the excellent correlation coefficient between Microsemi CRP and Micros CRP 200 ( r ≧ 0.992) as well as ADVIA 2120i ( r ≧ 0.957). MON (%) showed good correlation between Microsemi CRP and Micros CRP 200 ( r = 0.959), but lower correlation between Microsemi CRP and ADVIA 2120 i ( r = 0.471). CRP data showed the good correlation with HITACHI 7600 ( r ≧ 0.997) and Micros CRP 200 ( r ≧ 0.997). Conclusion From these findings, we concluded that Microsemi CRP seemed the convenient laboratory analyzer in the setting of point of care testing ( POCT ) especially at NICU or primary care unit.