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Evaluation of ICSH schistocyte measurement guidelines in F rance
Author(s) -
Lesesve J.F.,
El Adssi H.,
Watine J.,
Oosterhuis W.,
Régnier F.
Publication year - 2013
Publication title -
international journal of laboratory hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.705
H-Index - 55
eISSN - 1751-553X
pISSN - 1751-5521
DOI - 10.1111/ijlh.12092
Subject(s) - computer science
Summary Introduction The schistocytes are fragmented red blood cells mainly observed in the setting of hemolytic anemias where they remain an important criterion for the diagnosis. As the identification of these cells is still problematic, the I nternational C ouncil for S tandardization in H ematology ( ICSH ) set up a consensus report in N ovember, 2011. The F rench G roup of C ellular H ematology ( GFHC ) aimed to collect the opinion of French biologists directly confronted to schistocytes measurements, about these guidelines. Methods Among the 578 professionals, 169 (29%) answered to the 10 questions dealing with the identification and measurements of schistocytes as proposed by the ICSH . Results A consensus was reached for the urgent need of such guidelines documents, especially in the current background of the E uropean accreditation EN ISO 15189 rules. A traduction in native (French) language was warmly wished in order to facilitate the diffusion of the information. The pathologic threshold for the diagnosis of thrombotic microangiopathic anemia ( TMA ) (>1%) remained questionable. For half of the biologists, the new fragmented red blood cell ( FRC ) parameter recently provided by two manufacturers of automated blood cell counters was still doubtfull for routine use. Conclusion This survey assessed the impact of international ‘guidelines’ on the F rench biological community. The will to implement validated recommendations was strong, reflecting the awareness of the biologists to standardize the laboratory investigations.