Characterization of a novel  MICB  variant in an individual from the Chinese Uyghur population,  MICB*005:09 , by cloning and sequencing | Zendy

Tursun Mikrban | Zendy; Wang ZhenFang | Zendy; Guo WenTao | Zendy; Hasim Ayshamgul | Zendy; Tian Wei | Zendy

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Characterization of a novel MICB variant in an individual from the Chinese Uyghur population, MICB*005:09 , by cloning and sequencing

Author(s) -

Tursun Mikrban,

Wang ZhenFang,

Guo WenTao,

Hasim Ayshamgul,

Tian Wei

Publication year - 2019

Publication title -

international journal of immunogenetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.41

H-Index - 47

eISSN - 1744-313X

pISSN - 1744-3121

DOI - 10.1111/iji.12410

Subject(s) - sanger sequencing , biology , genetics , cloning (programming) , exon , allele , dna sequencing , gene , microbiology and biotechnology , computer science , programming language

Summary A new allelic variant in MICB*005 lineage, MICB*005:09 , has been identified in a male Uyghur individual recruited from Xinjiang Uyghur Autonomous Region, China by PCR‐sequence‐based typing (Sanger sequencing) and confirmed by cloning and sequencing. Aligned with MICB*005:03 , this new allelic variant shows a synonymous T substitution at nucleotide position 8 in exon 2, corresponding to codon 3 (CAC→CAT) of the mature MICB mRNA transcript.

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