z-logo
Premium
Distribution of ABO and RHD blood group antigens in blood donors in Burkina Faso
Author(s) -
Sawadogo Salam,
Nebie Koumpingnin,
Millogo Tieba,
Kafando Eléonore,
Sawadogo AbdoulGuyani,
Dahourou Honorine,
Traore Fauceny,
Ouattara Siaka,
Ouedraogo Oumarou,
Kienou Kisito,
Dieudonné Yonli Yentema,
Deneys Véronique
Publication year - 2019
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/iji.12408
Subject(s) - abo blood group system , allele , ethnic group , population , rh blood group system , phenotype , allele frequency , biology , blood type (non human) , demography , immunology , medicine , genetics , gene , antibody , environmental health , sociology , anthropology
Geographical distribution of ABO and RHD antigens is important for blood transfusion services and population genetics studies. There are few data on this topic in Burkina Faso, a multi‐ethnic country. Our study aims at reporting phenotypic and allelic frequencies of ABO and RHD blood groups among voluntary blood donors from various ethnical regions of Burkina Faso. We conducted a cross‐sectional study including 81,486 blood donors. ABO allelic frequencies were determined using the Bernstein method. Differences in phenotypic distribution of blood groups were assessed using the chi‐square test; a p value <0.05 being considered as statistically significant. We noticed that O+>B+>A+>AB+>O‐>B‐>A‐>AB‐ in our population. Phenotypic frequencies of blood groups A, B, O and AB were respectively 22.54%, 28.56%, 43.30% and 5.60%. RHD+was 92.24%. The allelic frequencies of A, B, O and D were respectively 0.1524; 0.1887; 0.6590 and 0.7214. We noticed statistical differences ( p  < 0.05) between these administrative regions which corresponded roughly to some natural ethnic areas. Indeed, the phenotype O was more frequent in the Central‐west, Central and East regions corresponding to “Mossi,” “Gourounsi,” “Gourmantché” areas while the phenotype A and AB were more reported in “Boucle du mouhoun” and “Hauts‐Bassins” regions where we have “Bwaba” and “Bobo.” The phenotype O negative was less frequent in “Bwaba.” Our study provides interesting information to blood services that will allow them to better refine their donor recruitment strategies.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here