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Frequency distribution of six cytokine gene polymorphisms in North‐ and South‐Italy
Author(s) -
Santovito A.,
Gendusa C.,
Matini A.,
Ferraro F.,
Musso I.,
Costanzo M.,
Delclos A.,
Cervella P.
Publication year - 2017
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/iji.12324
Subject(s) - allele frequency , gene , distribution (mathematics) , cytokine , genetics , biology , medicine , genotype , mathematics , mathematical analysis
Summary Allelic and genotype frequencies of four cytokine genes were obtained from 738 subjects from North‐ and South‐Italy. Populations were in Hardy–Weinberg equilibrium for all genes but significantly differed in the frequency of all SNP s and three haplotypes. In the MDS graph, they were plotted in separate positions close to Europeans and an Ivorian population, respectively.