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Vitamin D receptor gene polymorphisms association with the risk of sepsis and mortality
Author(s) -
Zeljic K.,
Elkilany A.,
Supic G.,
Surbatovic M.,
Djordjevic D.,
Magic Z.,
Bozic B.
Publication year - 2017
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/iji.12318
Subject(s) - foki , calcitriol receptor , sepsis , genotype , vitamin d and neurology , gene , medicine , biology , polymorphism (computer science) , genetics
Summary Association of vitamin D receptor (VDR) gene polymorphisms with sepsis risk and mortality was studied. VDR FokI CC genotype was associated with increased sepsis risk (OR = 13.396, p = .9) compared to the TT genotype. Results suggest possible role of VDR FokI (rs2228570) as a molecular biomarker of increased sepsis risk.
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