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A new MICA allele, MICA*007:07 , characterized by cloning and sequencing
Author(s) -
Wang W. Y.,
Tian W.,
Wang F.,
Zhu F. M.,
Wang P. X.,
Xing L. F.
Publication year - 2017
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/iji.12311
Subject(s) - mica , cloning (programming) , allele , genetics , polymerase chain reaction , biology , exon , mutation , microbiology and biotechnology , gene , paleontology , computer science , programming language
Summary A new MICA allelic variant, MICA*007:07 , was identified in an individual of Mongol ethnicity in the Inner Mongolia Autonomous Region, northern China. Following polymerase chain reaction‐sequence‐based typing (PCR‐SBT), this new allele was further confirmed by cloning and sequencing. MICA*007:07 differs from MICA*007:01 by a synonymous mutation from G to A at the 2nd nucleotide position in exon 2. MICA*007:07 was linked to HLA‐B*27:05 .