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A novel HLA ‐B*40 allele , B*40:01:40 , identified in a Chinese individual
Author(s) -
Pei Y. F.,
Huang H. N.,
Li H. C.,
Shen W. D.
Publication year - 2016
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/iji.12279
Subject(s) - allele , genetics , human leukocyte antigen , biology , typing , hla b , sequence (biology) , gene , antigen
Summary A new allele, officially named B*40:01:40 , was detected in a Chinese individual by sequence‐based typing ( SBT ). The new allele differs from B*40:01:01 by a single nucleotide exchange at position 99 in codon 9, which results in synonymous substitution and seems not to compromise the HLA complex and T‐cell receptor interaction.