z-logo
Premium
Identification of a novel MICB allele, MICB *030 , by cloning and sequencing
Author(s) -
Wang W. Y.,
Wang F.,
Tian W.
Publication year - 2015
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/iji.12207
Subject(s) - nonsynonymous substitution , cloning (programming) , biology , polymerase chain reaction , exon , allele , genetics , typing , microbiology and biotechnology , gene , genome , computer science , programming language
Summary A novel MICB allele, MICB *030 , has been identified in a healthy Chinese individual of Mongol ethnicity residing in northern China by polymerase chain reaction sequence‐based typing ( PCR ‐ SBT ) and confirmed by cloning and sequencing. MICB *030 was linked to HLA ‐B*35 . Aligned with MICB *005:02 , MICB *030 has a nonsynonymous adenine substitution at nucleotide position 50 in exon 3, leading to amino acid change from serine to arginine at codon 102 of the mature MICB molecule.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here