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IL ‐23R gene polymorphism rs2201841 is associated with psoriatic arthritis
Author(s) -
Popadic S.,
Ramic Z.,
Medenica Lj.,
Pravica V.,
Popadic D.
Publication year - 2014
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/iji.12127
Subject(s) - psoriatic arthritis , allele , psoriasis , medicine , arthritis , gene polymorphism , allele frequency , immunology , gene , gastroenterology , genetics , biology
Summary We examined rs2201841 within IL ‐23R gene in Serbian patients with psoriasis and healthy controls. G allele frequency was significantly increased in the group of patients with psoriatic arthritis compared with controls (0.481 vs 0.308). Carriage of G allele increases risk to develop psoriatic arthritis ( P = 0.009, OR = 3.311, 95% CI 1.29–8.70).
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