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HLA ‐G 5′ URR SNP s and 3′ UTR 14‐bp insertion/deletion polymorphism in an A fro‐ B razilian population from P araná S tate
Author(s) -
Tureck L. V.,
Santos L. C.,
Wowk P. F.,
Mattar S. B.,
Silva J. S.,
Magalhães J. C. M.,
Roxo V. M. M. S.,
Bicalho M. G.
Publication year - 2014
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/iji.12068
Subject(s) - haplotype , snp , polymorphism (computer science) , population , genetics , single nucleotide polymorphism , biology , gene , microbiology and biotechnology , allele , medicine , genotype , environmental health
Summary The present study investigated 23 SNP s in the 5′ URR promoter region and the 14 bp ins/del polymorphism at the 3′ UTR region of the HLA ‐ G gene in 150 individuals with A fro‐ B razilian ancestry. Three haplotypes were found to be the most frequent. Comparing these polymorphisms in other samples, our data suggest that Afro‐Brazilians are more similar to the Euro‐Brazilians than to Hutterite population.