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16th IHIW: International Histocompatibility Working Group in Hematopoietic Cell Transplantation
Author(s) -
Petersdorf E. W.,
Malkki M.,
Hsu K.,
Bardy P.,
Cesbron A.,
Dickinson A.,
Dubois V.,
Fleischhauer K.,
Kawase T.,
Madrigal A.,
Morishima Y.,
Shaw B.,
Spellman S.,
Spierings E.,
Stern M.,
Tiercy J.M.,
Velardi A.,
Gooley T.
Publication year - 2013
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/iji.12022
Subject(s) - histocompatibility , human leukocyte antigen , transplantation , histocompatibility testing , minor histocompatibility antigen , immunogenetics , immunology , major histocompatibility complex , biology , genetics , immune system , antigen , medicine
Summary The I nternational H istocompatibility W orking G roup is a collaborative international effort to understand the HLA and non‐ HLA genetics of the transplantation barrier. The W orking G roup is comprised of experts in the fields of histocompatibility and immunogenetics, hematopoietic cell transplantation and outcomes research. Data for 25 855 unrelated donor transplants were submitted in support of research studies for the 16th I nternational H istocompatibility W orkshop. Active investigation is in progress in seven key areas: the impact of HLA matching, role of race and ethnicity, identification of permissible HLA mismatches, haplotype‐associated determinants, minor histocompatibility antigens, immune response genes and KIR genetics. New hypotheses for the 16th workshop were developed for immunogenetic studies in cord blood and haploidentical‐related donor transplantation.