A conserved  HLA ‐A*02:28 associated  HLA  haplotype, A*02:28‐B*15:11‐ DRB 1*09:01, restricted to Taiwanese | Zendy

Yang K. L. | Zendy; Lee S. K. | Zendy; Lin P. Y. | Zendy

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A conserved HLA ‐A*02:28 associated HLA haplotype, A*02:28‐B*15:11‐ DRB 1*09:01, restricted to Taiwanese

Author(s) -

Yang K. L.,

Lee S. K.,

Lin P. Y.

Publication year - 2013

Publication title -

international journal of immunogenetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.41

H-Index - 47

eISSN - 1744-313X

pISSN - 1744-3121

DOI - 10.1111/iji.12005

Subject(s) - haplotype , human leukocyte antigen , biology , hematopoietic stem cell , typing , hla a , immunology , genetics , bone marrow , stem cell , haematopoiesis , allele , antigen , gene

Summary HLA ‐A*02:28, found in a Korean and a Japanese, was reported independently to the IMGT / HLA database in 2003 and 2005, respectively. We report here eight Taiwanese unrelated bone marrow hematopoietic stem cell donors carrying A*02:28 detected during our routine HLA typing exercise. The probable HLA ‐A, ‐B and ‐ DRB 1 haplotype in association with A*02:28 may be deduced from the eight marrow stem cell donor as A*02:28‐B*15:11‐ DRB 1*09:01. Our result suggests A*02:28‐B*15:11‐ DRB 1*09:01 is a conserved HLA haplotype restricted to Taiwanese.

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