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A conserved HLA ‐A*02:28 associated HLA haplotype, A*02:28‐B*15:11‐ DRB 1*09:01, restricted to Taiwanese
Author(s) -
Yang K. L.,
Lee S. K.,
Lin P. Y.
Publication year - 2013
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/iji.12005
Subject(s) - haplotype , human leukocyte antigen , biology , hematopoietic stem cell , typing , hla a , immunology , genetics , bone marrow , stem cell , haematopoiesis , allele , antigen , gene
Summary HLA ‐A*02:28, found in a Korean and a Japanese, was reported independently to the IMGT / HLA database in 2003 and 2005, respectively. We report here eight Taiwanese unrelated bone marrow hematopoietic stem cell donors carrying A*02:28 detected during our routine HLA typing exercise. The probable HLA ‐A, ‐B and ‐ DRB 1 haplotype in association with A*02:28 may be deduced from the eight marrow stem cell donor as A*02:28‐B*15:11‐ DRB 1*09:01. Our result suggests A*02:28‐B*15:11‐ DRB 1*09:01 is a conserved HLA haplotype restricted to Taiwanese.