Premium
Clinical aspects of egg bioactive peptide research: a review
Author(s) -
Grootaert Charlotte,
Voorspoels Stefan,
Jacobs Griet,
Matthijs Bea,
Possemiers Sam,
Van der Saag Hans,
Van Camp John,
Lucey Alice
Publication year - 2019
Publication title -
international journal of food science and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.831
H-Index - 96
eISSN - 1365-2621
pISSN - 0950-5423
DOI - 10.1111/ijfs.14139
Subject(s) - peptide , human health , hydrolysate , intervention (counseling) , clinical trial , computational biology , pharmacology , biology , medicine , bioinformatics , biochemistry , environmental health , psychiatry , hydrolysis
Summary Extensive in vitro and, to a more limited extent, animal research have demonstrated the health potential of a wide set of egg protein hydrolysates; however, well‐designed human intervention studies are scarce. Health claim assessment, however, sets high standards for characterisation of the bioactive peptides, investigation of the mode‐of‐action and convincing human intervention studies. In this review, we discuss the state‐of‐the‐art and knowledge gaps related to egg‐derived peptide bioavailability and bioactivity. In addition, we will formulate recommendations for appropriate design of future human intervention trials with egg‐derived peptides.