z-logo
Premium
Antioxidant and antitumour activities of exopolysaccharide from liquid‐cultured Grifola frondosa by chemical modification
Author(s) -
Zhang Wenna,
Lu Yongming,
Zhang Yaping,
Ding Qiuying,
Hussain Sajid,
Wu Qingxi,
Pan Wenjuan,
Chen Yan
Publication year - 2016
Publication title -
international journal of food science and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.831
H-Index - 96
eISSN - 1365-2621
pISSN - 0950-5423
DOI - 10.1111/ijfs.13059
Subject(s) - grifola frondosa , chemistry , antioxidant , polysaccharide , high performance liquid chromatography , hela , mushroom , food science , liquid culture , chromatography , biochemistry , biology , botany , in vitro
Summary Grifola frondosa is a popular edible mushroom for its tasty flavour and can be used as a dietary supplement for its functional substances. In this study, an exopolysaccharide ( EPS ), purified from the submerged culture of G. frondosa , was chemically modified to obtain its carboxymethylated ( CM ‐ EPS ) and selenising derivatives (Se‐ EPS ). The chemical characteristics of these polysaccharides were determined based on high‐performance liquid chromatography ( HPLC ) and infrared analysis ( IR ). The antioxidant and antitumour activities of EPS and its derivatives were further investigated, respectively. The results showed that the antioxidant capacity of CM ‐ EPS and Se‐ EPS were much better than that of EPS . Moreover, the Se‐ EPS could significantly inhibit the proliferation of Hela cells compared with EPS . This study demonstrated that the carboxymethylation and selenylation played a great influence on enhancing the antioxidant and antitumour activities of exopolysaccharides from G. frondosa .

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here