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Chitosan/tripolyphosphate‐nanoliposomes core‐shell nanocomplexes as vitamin E carriers: shelf‐life and thermal properties
Author(s) -
Xia Shuqin,
Tan Chen,
Xue Jin,
Lou Xiaowei,
Zhang Xiaoming,
Feng Biao
Publication year - 2014
Publication title -
international journal of food science and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.831
H-Index - 96
eISSN - 1365-2621
pISSN - 0950-5423
DOI - 10.1111/ijfs.12438
Subject(s) - chitosan , liposome , chemical engineering , thermostability , chemistry , membrane , coating , vitrification , dynamic light scattering , thermal stability , materials science , nanoparticle , nanotechnology , biochemistry , medicine , engineering , andrology , enzyme
Summary The aim of this study was to prepare the new core‐shell nanocomplexes as vitamin E (VE) carriers through chitosan (CS) coating onto the liposomal membrane surface in combination with sodium tripolyphosphate (TPP) cross‐linking, and investigated their storage and thermal properties by dynamic light scattering, ζ potential and fluorescence. Results showed that no obvious aggregation of nanocomplexes particles appeared and the VE retention rate was over 80% during the 30‐day storage. Thermal experiments demonstrated that the modification of polymers enhanced the stability of liposomes against temperature, including suppressing particle aggregation, ζ potential inversion and membrane fluidity. Compared with the great leakage of VE from uncovered liposomes, the retention rate of VE loaded into nanocomplexes remained around 92% and 97% after heated at 65 °C for 30 min and 80 °C for 16 s, respectively. The findings proved that these nanocomplexes can be employed to protect VE for extending shelf‐life and enhancing thermostability, and provide feasibility for commercial usage.