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Palmar Melanotic Macules
Author(s) -
Yesudian Patrick,
Premalatha Subramaniam,
Thambiah Arthur S.
Publication year - 1984
Publication title -
international journal of dermatology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/ijd.1984.23.7.468
Subject(s) - medicine , general hospital , government (linguistics) , dermatology , family medicine , philosophy , linguistics
Multiple melanotic macules of varying sizes were present on the palmar surfaces of 42 of 50 consecutive South Indian patients with von Recklinghausen's disease. The histologic characteristics of the macules showed localized areas of fingerlike prolongations of the rete ridges with increased pigmentation of the basal cells. This epidermal change overlies a small neurofibroma accompanied by thick-walled blood vessels in the reticular dermis. A clinicopathologic correlation of these palmar melanotic macules constitutes yet another frequent and specific marker of classical neurofibromatosis.