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Inhibition of Hypophysial Activity by Paraoxypropiophenone in Acne Vulgaris
Author(s) -
Kantner A.
Publication year - 1965
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/ijd.1965.4.1.9
Subject(s) - acne , medicine , hormone , endocrinology , testosterone (patch) , androgen , dermatology
Summary The administration of paraoxypropiophenone failed to influence theso–called sebotrophic factor. Paraoxypropiophenone, in fact,inhibited at least the production of the gonadotrophic hormone(FSH). Results favor the hormonal theory of the origin of acne—a relative increase in the androgen level. Experiments will have to be continued and results will have to be followed longer after administration of gonadotrophic hormone in acne.