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Dermatological adverse reactions after vaccination with BNT162b2 in a cohort of healthcare workers
Author(s) -
RuizVillaverde Ricardo,
RiveraIzquierdo Mario,
GilVillalba Ana,
PegalajarGarcía Maria D.,
PérezRojas Javier,
SolerIborte Eva,
ValeroUbierna M Carmen
Publication year - 2022
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/ijd.16336
Subject(s) - medicine , vaccination , adverse effect , regimen , health care , rash , population , observational study , pediatrics , immunology , environmental health , economics , economic growth
Background The description of the skin reactions produced by the different vaccines against SARS‐CoV‐2 has focused on the symptoms reported by the general population. There are few studies with very different measurement methods focused on healthcare workers. Methods A longitudinal observational study was conducted on all the healthcare workers from the Hospital Universitario San Cecilio that received vaccination against COVID‐19 with BNT162b2. The recruitment period was from December 2020 to September 2021. The recommended regimen was double, with a minimum interval of 21 days between doses. All dermatological reactions reported as adverse effects of the vaccine were evaluated by the Staff of the Dermatology Unit of our center. Results A total of 3969 healthcare workers of our center were followed. Only 0.7% of them reported dermatological adverse reactions. The most frequently reported reactions were morbilliform rash and COVID arm. In the multivariate analysis, the vaccination regimen (one dose) and the history of COVID‐19 infection remained the main factors associated with the report of dermatological adverse reactions. Conclusion The rate of dermatological adverse reactions after vaccination with BNT162b2 (Pfizer‐BioNTech) is extraordinarily low. No patient required hospitalization, which supports the safety of this vaccination in a population of healthcare workers.