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Primary cutaneous lymphoma in Argentina: a report of a nationwide study of 416 patients
Author(s) -
Abeldaño Alejandra,
Enz Paula,
Maskin Matias,
Cervini Andrea B.,
Torres Natallia,
Acosta Ana C.,
Narbaitz Marina,
Vanzulli Silvia,
Orentrajch Mirta,
Villareal Marta A.,
Garcia Pazos Maria L.,
Arias Mariana,
Zambrano Franco Evelyn A.,
Fontana Maria I.,
Chuit Roberto
Publication year - 2019
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/ijd.14262
Subject(s) - medicine , mycosis fungoides , cutaneous lymphoma , lymphoma , cbcl , dermatology , clinical psychology
Background The aim of this study was to determine the relative frequency of primary cutaneous lymphoma (PCL) in Argentina according to the new World Health Organization (WHO)‐European Organization for the Research and Treatment of Cancer (EORTC) classification system. Methods A total of 416 patients from 21 dermatology services were included during a 5‐year period (2010–2015); these patients were classified using WHO‐EORTC criteria. Results There were 231 (55.2%) males and 185 (44.8%) females; the male‐to‐female ratio was 1.35. The median age of the patients was 57 years (range, 0–90 years). Most patients were Caucasian (79%), and only 16% of patients were registered as Amerindian. Most patients (387/416, 93%) had cutaneous T‐cell lymphoma (CTCL); 28 patients (6.7%) were diagnosed with cutaneous B‐cell lymphoma (CBCL). The most frequent CTCL subtypes, in decreasing order of prevalence, were mycosis fungoides (MF), including its variants (75.7%); CD30+ primary cutaneous lymphoproliferative disorders (7.2%); and Sézary syndrome (SS) (3.1%). Cutaneous follicle center lymphoma was the most common CBCL subtype (2.9%). In the subset of patients ≤20 years of age, the most common condition was MF (57%), followed by extranodal NK‐T nasal‐type lymphoma (14%). Conclusions This study revealed relatively higher rates of MF and lower rates of CBCL in Argentinean patients that have been reported in American and European countries.

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