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Lactic and lactobionic acids as typically moisturizing compounds
Author(s) -
AlgiertZielińska Barbara,
Mucha Paulina,
Rotsztejn Helena
Publication year - 2019
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/ijd.14202
Subject(s) - medline , lactic acid , medicine , web of science , antioxidant , biochemistry , chemistry , biology , bacteria , genetics
Background Recently more attention has been drawn to alpha hydroxy and polyhydroxy acids ( AHA and PHA ) due to their excellent moisturizing and antioxidant properties. These compounds are very beneficial in terms of both cosmetic and dermatological treatments. Objective The aim of this study was an assessment of moisturizing properties of lactobionic and lactic acids based on available literature. Methods Literature review using scientific databases: PubMed, Medline ( EBSCO ), Medline Complete, Karger, Springer/ ICM , SpringerLink/online, Wiley Online Library. Results and Conclusions Through their construction, alpha AHA and PHA are able to bind large amounts of water and act as potent antioxidant agents through inhibition of matrix metalloproteinases and strong chelating properties. Another important characteristic is the maintenance of the epidermal barrier integrity during application of lactic acid ( LAC ) and lactobionic acid ( LA ) and thus the opportunity to use them on sensitive skin types including couperose skin.