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Motor nerve conduction velocity is affected in segmental vitiligo lesional limbs
Author(s) -
Zhou Jun,
Zhong Zhenyu,
Li Jian,
Fu Wenwen
Publication year - 2016
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/ijd.13171
Subject(s) - medicine , nerve conduction velocity , motor nerve , sensory nerve , compound muscle action potential , anatomy , median nerve , sensory system , electrophysiology , neuroscience , biology
To evaluate the effects of segmental vitiligo (SV) on nerve conduction velocity (NCV) in different nerves, we compared the patient's lesional side of their body to the contralateral normal side. The 106 participants were selected from outpatients visiting the dermatological clinics of H uashan H ospital, F udan U niversity, from N ovember 2011 to M arch 2014. NCV s were measured on the limbs and the face, including both motor and sensory nerves. The parameters for NCV s included motor nerve conduction velocity ( MCV ) and its distal conduction latency, sensory nerve conduction velocity, sensory nerve action potentials amplitude, and compound muscle action potential amplitude. MCV on the limbs was compromised by SV state, which was significantly slower on the lesional side of the body compared with the normal contralateral side ( P = 0.006). Furthermore, SV at the stable stage significantly impaired MCV compared with the SV at progressive stage. There was no significant difference in the other parameters of NCV between lesional and normal sides of the body. Compound muscle action potentials in the face did not differ between lesional and healthy sides. Motor nerves in the limbs were compromised by SV , particularly when the disease was at the stable stage.