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Incidence of Merkel cell carcinoma in Olmsted County, Minnesota: a population‐based study
Author(s) -
Chang Michael B.,
Weaver Amy L.,
Brewer Jerry D.
Publication year - 2016
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/ijd.12812
Subject(s) - rochester epidemiology project , medicine , incidence (geometry) , merkel cell carcinoma , epidemiology , demography , population , surveillance, epidemiology, and end results , carcinoma , cancer registry , population based study , environmental health , physics , sociology , optics
Background Merkel cell carcinoma ( MCC ) is a rare, aggressive, often cutaneous malignancy. The incidence has been estimated from national registries in the USA and elsewhere, and data indicate variations depending on the region studied. The objective of this study was to determine the incidence of MCC in Olmsted County ( MN , USA ). Methods Using the Rochester Epidemiology Project, which contains health records for all the residents of Olmsted County, we retrospectively reviewed the records for all cases of MCC from 1976 to 2011. Results The overall annual age‐ and sex‐adjusted incidence of MCC in Olmsted County during 1976–2011 was 0.35 per 100,000 person‐years (95% CI , 0.14–0.57). The incidence tended to be higher among men than women with 0.69 per 100,000 (95% CI , 0.24–1.14) and 0.10 per 100,000 (95% CI , 0–0.24), respectively. Conclusions These data are within the range of previous MCC incidence reports, and the incidence of MCC in Olmsted County is consistent with rates reported in the remainder of the USA .