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Treatment of facial lipoatrophy with polymethylmethacrylate among patients with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS): impact on the quality of life
Author(s) -
Quintas Rodrigo C. S.,
França Emmanuel R.,
Petribú Kátia C. L.,
Ximenes Ricardo A. A.,
Quintas Lóren F. F. M.,
Cavalcanti Ernando L. F.,
Kitamura Marco A. P.,
Magalhães Kássia A. A.,
Paiva Késsia C. F.,
Filho Demócrito B. Miranda
Publication year - 2014
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/ijd.12400
Subject(s) - medicine , lipodystrophy , beck depression inventory , quality of life (healthcare) , lipoatrophy , ecchymosis , visual analogue scale , stavudine , depression (economics) , adverse effect , surgery , dermatology , human immunodeficiency virus (hiv) , viral load , antiretroviral therapy , anxiety , psychiatry , immunology , nursing , economics , macroeconomics
Background The lipodystrophy syndrome is characterized by selective loss of subcutaneous fat on the face and extremities (lipoatrophy) and/or accumulation of fat around the neck, abdomen, and thorax (lipohypertrophy). The aim of this study has been to assess the impact of polymethylmethacrylate facial treatment on quality of life, self‐perceived facial image, and the severity of depressive symptoms in patients living with HIV / AIDS . Methods A non‐randomized before and after interventional study was developed. Fifty‐one patients underwent facial filling. The self‐perceived quality of life, facial image, and degree of depressive symptoms were measured by the Short‐Form 36 and HIV / AIDS – Targeted quality of life questionnaires, by a visual analogue scale and by the Beck depression inventory, respectively, before and three months after treatment. Results Six of the eight domains of Short‐Form 36 and eight of the nine dimensions of the HIV / AIDS – Targeted quality of life questionnaires, together with the visual analogue scale and by the Beck depression inventory scores, revealed a statistically significant improvement. The only adverse effects registered were edema and ecchymosis. Conclusion The treatment of facial lipoatrophy improved the self‐perceived quality of life and facial image as well as any depressive symptoms among patients with HIV / AIDS .