z-logo
Premium
Pediatric S weet syndrome. A retrospective study
Author(s) -
GarcíaRomero Maria Teresa,
Ho Nhung
Publication year - 2015
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/ijd.12372
Subject(s) - medicine , dapsone , malignancy , retrospective cohort study , sweet syndrome , dermatology , surgery , gastroenterology , pediatrics
Sweet syndrome ( SS ) is a relatively rare pediatric diagnosis, with fewer than 80 pediatric cases reported in the literature, characterized by tender erythematous plaques and nodules associated with systemic inflammation. Materials and methods We retrospectively reviewed the charts of pediatric patients diagnosed with SS both clinically and histologically at our reference hospital between the years of 2000 and 2012. Clinical, laboratory, and pathologic data were analyzed. Results We found five patients; four were male, aged between 9 and 14 years. All had fever, elevated markers of systemic inflammation, and typical skin lesions. SS was associated with underlying hematologic malignancy in one patient; all‐ trans retinoic acid in another; infection in two patients; and in one patient, no identifiable cause was found. Three of the five patients treated with systemic corticosteroids had excellent response, and two had recurrences and received additional treatment with dapsone and saturated solution of potassium iodide. Conclusions Sweet syndrome is an extremely rare diagnosis in children. It is associated with the same conditions as in adults, but it is more frequently associated with infections than malignancies. In general, prognosis is good, but recurrences occur and second‐line treatment may be needed.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here