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Malignancies of the eyelid: a review of primary and metastatic cancers
Author(s) -
Dekmezian Mhair S.,
Cohen Philip R.,
Sami Mirwat,
Tschen Jaime A.
Publication year - 2013
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/ijd.12089
Subject(s) - medicine , eyelid , biopsy , pathology , dermatology , immunostaining , presentation (obstetrics) , natural history , radiology , immunohistochemistry
The eyelid can be the site of various malignant tumors, including epithelial, mesenchymal, lymphoproliferative, and endocrine neoplasms, all of which can present in unusual ways or mimic benign processes, often requiring biopsy for a definitive diagnosis. This review article presents a broad overview of some of the malignancies that have been reported to occur in eyelids, addressing clinical presentation and natural history, histologic and immunostaining characteristics, and genetic associations where relevant. The unique combination of functional importance, to protect and lubricate the eye, and cosmetic importance make management of eyelid lesions difficult. We describe a few of the diagnostic and treatment options that can be considered.