Open AccessCorrelation between chest CT severity score and laboratory indicators in patients with Coronavirus disease 2019 (COVID‐19)
Author(s) -
Lin Qunying,
Wu Liangning,
Lin Weihua,
Zhu Linjian,
Hu Yuxiong,
Lin Guosheng,
Lin Juan,
Tu Haijian
Publication year - 2021
Publication title -
international journal of clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 98
eISSN - 1742-1241
pISSN - 1368-5031
DOI - 10.1111/ijcp.14907
Subject(s) - medicine , covid-19 , coronavirus , severity of illness , betacoronavirus , disease , coronavirus infections , pathology , infectious disease (medical specialty) , outbreak
Objective The association between computed tomography (CT) and clinical severity of COVID‐19 has been demonstrated. However, there are few studies on CT and laboratory indicators in patients in COVID‐19. Our aim was to explore the correlation between chest CT images and laboratory indicators of patients with COVID‐19 pneumonia. Methods This was a retrospective study of patients with COVID‐19 diagnosed and treated at the Affiliated Hospital of Putian University from 24 January 2020 to 6 March 2020. The correlation test between first chest CT score and blood cell analysis, C‐reactive protein (CRP), erythrocyte sedimentation rate (ESR), blood biochemistry and T lymphocyte subsets (T‐Ls) was investigated. Results Among the 56 patients, there were 36 (64.3%) males and 20 (35.7%) females. The mean age of the patients was 46.54 ± 15.82 (range, 15‐86) years. The CT score in the moderate group was higher than in the mild group (5.06 ± 0.77 vs 1.87 ± 0.88, P < .05), and higher in the severe group than in the moderate and mild groups (10.71 ± 4.21, P < .05). In addition, the ESR was significantly higher in the severe group than mild group (32.00 (26.04, 58.24) vs 11.00 (7.84, 24.70) mm/h, P < .05). The CD3, CD4, CD8 and CD4/CD8 cells were not different (all P > .05). The CT scores of all patients correlated positively with CRP, LDH and ESR (all P < .01). Conclusion The chest CT characteristics of patients with COVID‐19 correlated positively with CRP, ESR and LDH, which may use one of the indicators for the assessment of disease severity.