Open AccessRelationship between chest CT scan findings with SOFA score, CRP, comorbidity, and mortality in ICU patients with COVID‐19
Author(s) -
Hejazi Mohammad Esmaeil,
Malek Mahdavi Aida,
Navarbaf Zahra,
Tarzamni Mohammad Kazem,
Moradi Rozhin,
Sadeghi Armin,
Valizadeh Hamed,
Namvar Leila
Publication year - 2021
Publication title -
international journal of clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 98
eISSN - 1742-1241
pISSN - 1368-5031
DOI - 10.1111/ijcp.14869
Subject(s) - medicine , comorbidity , intensive care unit , sofa score , overweight , covid-19 , computed tomography , malignancy , radiology , obesity , disease , infectious disease (medical specialty)
Abstract Objective This study aimed to investigate the relationship between chest computed tomography (CT) scan findings with sequential organ failure assessment (SOFA) score, C‐reactive protein (CRP), comorbidity, and mortality in intensive care unit (ICU) patients with coronavirus disease 19 (COVID‐19). Method Adult patients (≥18 years old) with COVID‐19 who were consecutively admitted to the Imam‐Reza Hospital, Tabriz, East‐Azerbaijan Province, North‐West of Iran between March 2020 and August 2020 were screened and total of 168 patients were included. Demographic, clinical, and mortality data were gathered. Severity of disease was evaluated using the SOFA score system. CRP levels were measured and chest CT scans were performed. Results Most of patients had multifocal and bilateral ground glass opacity (GGO) pattern in chest CT scan. There were significant correlations between SOFA score on admission with multifocal and bilateral GGO ( P = .010 and P = .011, respectively). Significant relationships were observed between unilateral and bilateral GGO patterns with CRP ( P = .049 and P = .046, respectively). There was significant relationship between GGO patterns with comorbidities including overweight/obesity, heart failure, cardiovascular diseases, and malignancy ( P < .05). No significant relationships were observed between chest CT scan results with mortality ( P > .05). Conclusion Multifocal bilateral GGO was the most common pattern. Although chest CT scan characteristics were significantly related with SOFA score, CRP, and comorbidity in ICU patients with COVID‐19, a relationship with mortality was not significant.