Open AccessMonocyte to high‐density lipoprotein cholesterol and lymphocyte to monocyte ratios are predictors of in‐hospital and long‐term mortality in patients with acute coronary syndrome
Author(s) -
Oylumlu Muhammed,
Oylumlu Mustafa,
Arik Baran,
Demir Muhammed,
Ozbek Mehmet,
Arslan Bayram,
Acun Baris,
Polat Nihat,
Akil Mehmet Ata,
Bilik Mehmet Zihni
Publication year - 2021
Publication title -
international journal of clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 98
eISSN - 1742-1241
pISSN - 1368-5031
DOI - 10.1111/ijcp.13973
Subject(s) - medicine , acute coronary syndrome , monocyte , gastroenterology , lymphocyte , myocardial infarction
Objective We aimed to determine the relationship between LMR and MHR and in‐hospital and long‐term mortality in patients with ACS. Methods We retrospectively collected patients with ACS undergoing coronary angiography between January 2012 and December 2013. Results In total, 825 patients with a mean age of 62.4 ± 12.9 years (71.3% male) were enrolled in the study. Patients were divided into three tertiles based on MHR levels and LMR levels. In‐hospital mortality of the patients was significantly higher amongst patients in the upper MHR tertile when compared with the lower and middle MHR tertile groups [30 (10.9%) vs 8 (2.9%) and 14 (5.1%); P < .001, P = .009, respectively]. Five‐year mortality of the patients was significantly higher amongst patients in the upper MHR tertile when compared with the lower and middle MHR tertile groups [84 (30.5%) vs 48 (17.5%) and 57 (20.7%); P < .001, P = .005, respectively]. In‐hospital mortality of the patients was significantly higher amongst patients in the lower LMR tertile when compared with the upper and middle LMR tertile groups [25 (9.1%) vs 10 (3.6%) and 17 (6.2%); P = .007, P = .130, respectively]. Five ‐year mortality of the patients was significantly higher amongst patients in the lower LMR tertile when compared with the upper and middle LMR tertile groups [77 (28.0%) vs 47 (17.1%) and 65 (23.6%); P = .001, P = .142, respectively]. Conclusion We have shown that high MHR and low LMR were significant and independent predictors of in‐hospital and long‐term mortality in patients with ACS.