Open AccessInpatient burden and mortality of heatstroke in the United States
Author(s) -
Kaewput Wisit,
Thongprayoon Charat,
Petnak Tananchai,
Cato Liam D.,
Chewcharat Api,
Boonpheng Boonphiphop,
Bathini Tarun,
Vallabhajosyula Saraschandra,
Cheungpasitporn Wisit
Publication year - 2021
Publication title -
international journal of clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 98
eISSN - 1742-1241
pISSN - 1368-5031
DOI - 10.1111/ijcp.13837
Subject(s) - heatstroke , medicine , emergency medicine , rhabdomyolysis , logistic regression , mortality rate , mechanical ventilation , complication , intensive care medicine , pediatrics
Background This study aimed to assess inpatient prevalence, characteristics, outcomes, and resource utilisation of hospitalisation for heatstroke in the United States. Additionally, this study aimed to explore factors associated with in‐hospital mortalities of heatstroke. Methods The 2003‐2014 National Inpatient Sample database was used to identify hospitalised patients with a principal diagnosis of heatstroke. The inpatient prevalence, clinical characteristics, in‐hospital treatments, outcomes, length of hospital stay, and hospitalisation cost were studied. Multivariable logistic regression was performed to identify independent factors associated with in‐hospital mortality. Results A total of 3372 patients were primarily admitted for heatstroke, accounting for an overall inpatient prevalence of heatstroke amongst hospitalised patients of 36.3 cases per 1 000 000 admissions in the United States with an increasing trend during the study period ( P < .001). Age 40‐59 was the most prevalent age group. During the hospital stay, 20% required mechanical ventilation, and 2% received renal replacement therapy. Rhabdomyolysis was the most common complication. Renal failure was the most common end‐organ failure, followed by neurological, respiratory, metabolic, hematologic, circulatory, and liver systems. The in‐hospital mortality rate of heatstroke hospitalisation was 5% with a decreasing trend during the study period ( P < .001). The presence of end‐organ failure was associated with increased in‐hospital mortality, whereas more recent years of hospitalisation was associated with decreased in‐hospital mortality. The median length of hospital stay was 2 days. The median hospitalisation cost was $17 372. Conclusion The inpatient prevalence of heatstroke in the United States increased, while the in‐hospital mortality of heatstroke decreased.