Open AccessIncidence and case fatality rate of COVID‐19 in patients with inflammatory articular diseases
Author(s) -
Mena Vázquez Natalia,
ManriqueArija Sara,
CabezudoGarcía Pablo,
GodoyNavarrete Francisco Javier,
CabezasLucena Alba María,
MoralesÁguila M.,
RedondoRodríguez Roció,
Sobrino Beatriz,
UreñaGarnica Inmaculada,
OrdoñezCañizares M. C.,
Díaz CordovésRego Gisela,
FernándezNebro Antonio
Publication year - 2021
Publication title -
international journal of clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 98
eISSN - 1742-1241
pISSN - 1368-5031
DOI - 10.1111/ijcp.13707
Subject(s) - medicine , case fatality rate , incidence (geometry) , cumulative incidence , population , risk factor , logistic regression , rheumatoid arthritis , epidemiology , cohort , environmental health , optics , physics
Objective To describe the incidence and fatality of coronavirus disease 2019 (COVID‐19) and identify risk factors to fatality in patients with inflammatory articular diseases (IAD). Methods This is a cross‐sectional observational study of IAD patients and COVID‐19 with controls matched for age, sex, and RT‐PCR. A control group was used to compare the cumulative incidence (CI) and case fatality rate (CFR). The main outcomes of the study were CI and CFR. Other variables included comorbidities, treatments, and characteristics of the COVID‐19. Multiple logistic regression analysis was performed to investigate risk factors for fatality in patients with IAD. Results Of the 1537 patients who fulfilled the inclusion criteria, 23/1537 (1.49%) had IAD 13 (0.8%) had rheumatoid arthritis (RA), 5 psoriatic arthritis (PsA) (0.3%) and 5 axial spondyloarthritis (0.3%). There were no significant differences in CI of COVID‐19 and CFR in patients with IAD compared with COVID‐19 patients without IAD. In RT‐PCR positive patients, the CI of COVID‐19 in PsA and AS was higher. Of the 23 IAD patients, 2 RA patients (8.6%) died. The patients did no show characteristics of the COVID‐19 disease different from the population. In multivariate analysis, the factor associated with fatality in patients with IAD was older age (OR [95% CI], 1.1 [1.0‐1.2]). Conclusion COVID‐19 CI, fatality rate and other features do not seem to be increased in IAD patients. Older age was associated with fatality in patients with IAD.