Open AccessPrognostic factors for surgical margin status and recurrence in partial nephrectomy
Author(s) -
Demirel Hüseyin C.,
Çakmak Sedat,
Yavuzsan Abdullah H.,
Yeşildal Cumhur,
Türk Semih,
Dalkılınç Ayhan,
Kireççi Sinan L.,
Tokuç Emre,
Horasanlı Kaya
Publication year - 2020
Publication title -
international journal of clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 98
eISSN - 1742-1241
pISSN - 1368-5031
DOI - 10.1111/ijcp.13587
Subject(s) - medicine , nephrectomy , surgical margin , pathological , stage (stratigraphy) , magnetic resonance imaging , renal mass , surgery , radiology , kidney , resection , paleontology , biology
Purpose To evaluate the prognostic factors affecting the surgical margin and recurrence in patients who underwent partial nephrectomy (PN) for renal masses. Materials and Methods Data of 125 patients who underwent open or laparoscopic PN because of renal mass between January 2006 and January 2019 were analysed retrospectively. Demographic data, habits, additional diseases, clinical and laboratory findings, operational data, the morphology of the tumour in computerised tomography or magnetic‐resonance imaging and follow‐up data were scanned and acquired via our hospital's system and archive. Results Average age was 54.4, male‐female ratio was 1.55 and average tumour size was 3.31 cm. One hundred and four patients had malignant pathology and 21 were benign. Positive surgical margin (PSM) rate was 5.6% and recurrence rate was 3.2%. Average follow‐up was 47.4 months. Pathological size of the tumour was larger ( P = .006), warm‐ischemia period was lower ( P = .003) and PADUA score was higher ( P = .015) in open technique. Tumour size and tumour stage were statistically higher in patients with recurrence ( P = .009, P < .001, respectively). There was a significantly higher PSM ratio in mandatory indication group than elective indication group ( P = .025). No statistically significant difference was observed between surgical margin positivity and tumour size, Fuhrman grades, PADUA scores, RENAL scores and C‐index. ( P > .05). Conclusion Surgical margin positivity after PN is not significantly associated with tumour characteristics and anatomical scoring systems. Surgical indication for PN has a direct influence on PSM rates. Tumour size and stage after PN are valuable parameters in evaluating the recurrence risk.