Open AccessRates, predictors and the impact of cannabis misuse on in‐hospital outcomes among patients undergoing percutaneous coronary intervention (from the National Inpatient Sample)
Author(s) -
Kwok Chun Shing,
Alraies M. Chadi,
Mohamed Mohamed,
Rashid Muhammad,
Shoaib Ahmad,
Nolan James,
Ratib Karim,
Khoo Chee W.,
Kontopantelis Evangelos,
Mamas Mamas A.
Publication year - 2020
Publication title -
international journal of clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 98
eISSN - 1742-1241
pISSN - 1368-5031
DOI - 10.1111/ijcp.13477
Subject(s) - medicine , cannabis , conventional pci , percutaneous coronary intervention , quartile , odds ratio , stroke (engine) , confidence interval , psychiatry , myocardial infarction , mechanical engineering , engineering
Background Whether cannabis use worsens outcomes in coronary heart disease is unknown and no previous study has evaluated the outcomes for patients who undergo percutaneous coronary intervention (PCI) according to cannabis use. Methods We analysed patients in the National Inpatient Sample between 2004 and 2014 who underwent PCI and evaluated rates, predictors and outcomes of patients according to cannabis misuse defined by cannabis abuse or dependence. Results A total of 7 306 012 patients were included and 32 765 cannabis misusers (0.4%). Cannabis misusers were younger (49.5 vs 64.6 years, P < .001) and were more likely to be male (82.7% vs 66.3%, P < .001). There was also a greater proportion of patients who were of black ethnicity in the cannabis misuse group (27.7% vs 7.9%, P < .001) and fewer elective admissions (7.8% vs 27.6%, P < .001). There was no difference in in‐hospital mortality (OR 1.06 95% CI 0.80‐1.40, P = .67), bleeding (OR 0.94 95% CI 0.77‐1.15, P = .55) and stroke/transient ischaemic attack (OR 1.19 95% CI 0.98‐1.45, P = .084) compared with non‐cannabis misusers. Cannabis misusers had significantly lower odds of in‐hospital vascular complications (OR 0.73 95% CI 0.58‐0.90, P = .004). Conclusions Our results suggest that cannabis misusers are more likely to be male, of black ethnicity and from the lowest quartile of income, but there was no evidence that cannabis misuse is associated with worse periprocedural outcomes following PCI when controlling for key proxies of health status.