Open AccessNocturia is more bothersome than daytime LUTS : Results from an Observational, Real‐life Practice Database including 8659 European and American LUTS patients
Author(s) -
Everaert Karel,
Anderson Peter,
Wood Robert,
Andersson Fredrik L.,
HolmLarsen Tove
Publication year - 2018
Publication title -
international journal of clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 98
eISSN - 1742-1241
pISSN - 1368-5031
DOI - 10.1111/ijcp.13091
Subject(s) - nocturia , medicine , lower urinary tract symptoms , overactive bladder , quality of life (healthcare) , observational study , medical diagnosis , urology , population , urinary system , alternative medicine , prostate , radiology , nursing , environmental health , pathology , cancer
Summary Purpose Lower urinary tract symptoms ( LUTS ) encompass several diagnoses, including overactive bladder ( OAB ) and benign prostatic hyperplasia ( BPH ). Nocturia is a standalone symptom, but also included in OAB and BPH . Current discussion addresses whether the overlap of the diagnoses is too broad, leading to misdiagnosis. This study explored the differences in level, causes and consequences for patients with a diagnosis of daytime LUTS compared with a diagnosis of nocturia, and discussed whether people are being treated for the symptoms that truly bother them the most. Patients and methods Data were drawn from a survey of physicians and patients in France, Germany, Spain, UK and USA . Physicians filled out patient record forms ( PRF s) for patients with LUTS diagnosis. The patients completed the patient self‐completion form ( PSC ). Three PRO questionnaires were included; the OAB ‐q SF , NI ‐Diary and WPAI . Patients were grouped based on the diagnoses assigned to them by their physicians in a real‐life setting. Results Eight thousand seven hundred and thirty eight patients had a LUTS diagnosis and 5335 completed a PSC . Patients diagnosed with night‐time symptoms were significantly more bothered by their LUTS than only daytime LUTS patients (all questionnaires P < .0001). Patients with nocturia reported being tired “always” or “usually” more often than patients with daytime problems only ( P < .0001). Only 13% of patients with nocturia had an initial sleep period of more than 2‐3 hours. Conclusion In this population of real‐life patients, those with a diagnosis of nocturia reported significantly higher impact on their quality of life than patients with a diagnosis of daytime LUTS only. The underlying causes of bother were related to sleep problems. It is essential that nocturia is understood, treated and monitored as a distinct problem from OAB and BPH , to ensure that patients are treated for their main symptom.