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Biowaste‐derived hydroxyapatite reinforced with polyvinyl pyrrolidone/aloevera composite for biomedical applications
Author(s) -
Mathina Mathiyalagan,
Shinyjoy Elangomannan,
Kavitha Louis,
Gopi Dhanaraj
Publication year - 2020
Publication title -
international journal of applied ceramic technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 57
eISSN - 1744-7402
pISSN - 1546-542X
DOI - 10.1111/ijac.13630
Subject(s) - biocompatibility , materials science , composite number , biocomposite , fourier transform infrared spectroscopy , polyvinylpyrrolidone , biopolymer , biomaterial , antibacterial activity , chemical engineering , composite material , polymer , scanning electron microscope , nuclear chemistry , polymer chemistry , nanotechnology , chemistry , biology , bacteria , engineering , metallurgy , genetics
The present investigation focuses on the synthesis of crabshell‐derived hydroxyapatite (CS‐HAP)/ water‐soluble synthetic polymer—polyvinylpyrrolidone(PVP)/aloevera(AV)—a natural biopolymer, as a composite for enhanced mechanical, antibacterial and biocompatible properties. The reinforcement of polymer has a significant function in increasing the mechanical property of the composite, whereas the incorporation of AV improves the antibacterial and biocompatibility. Phase composition, morphology, mechanical property, and hydrophilicity of CS‐HAP/PVP/AV biocomposite with different concentrations of PVP and AV were examined by Fourier transform infrared spectroscopy (FTIR), X‐Ray diffraction (XRD), scanning electron microscopy with energy dispersive X‐ray (SEM‐EDX), Vickers microhardness tests, contact angle, respectively. Furthermore, the antibacterial efficiency of the composite is assessed using Escherichia coli ( E coli ) and Staphylococcus aureus ( S aureus ). The biocompatibility of HOS MG 63 cells on the CS‐HAP/PVP/AV composite is evaluated by MTT assay test. The obtained results evidence that the as‐synthesized composite have appropriate mechanical, antibacterial and biocompatible properties. Overall, the combination of mechanical property of PVP, antibacterial and biocompatible property of AV in CS‐HAP/PVP/AV, makes the composite a potential therapeutic material for various biomedical applications.