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Meteoric synthesis of Luminescent Fe 2 O 3 Nanoparticles: A potential Cytotoxic, Antioxidant & Bactericidal agent
Author(s) -
Deepthi Reddy Gavini,
Noorjahan Mohammed,
Ratnamala Annapragada,
Haseena Mohammed,
Manjunatha Hanumanthrayappa,
Chandra Babu Naidu Kadiyala
Publication year - 2020
Publication title -
international journal of applied ceramic technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 57
eISSN - 1744-7402
pISSN - 1546-542X
DOI - 10.1111/ijac.13591
Subject(s) - hela , nuclear chemistry , materials science , bacillus subtilis , antioxidant , mtt assay , dpph , nanoparticle , luminescence , cytotoxicity , bacteria , nanotechnology , chemistry , organic chemistry , biochemistry , cell growth , biology , cell , in vitro , genetics , optoelectronics
Here we report the meteoric synthesis of luminescent nanomagnetic Fe 2 O 3 (LNM Fe 2 O 3 ) particles using green sources ie, microwave energy of 800 W and Hibiscus rosasinensis (H rosasinensis) leaf extract with high anti oxidant and anti cancer properties as an active surfactant. The microwave irradiation times for the synthesis of LNM Fe 2 O 3 particles were optimized. Structural morphology, magnetic and optical properties of synthesized LNM Fe 2 O 3 particles was studied using different analytical techniques. The data clearly indicated that H rosasinensis leaf extract‐mediated LNM Fe 2 O 3 particles are spherical in shape with the presence of both α‐Fe 2 O 3 and small amounts of ϒ ‐ Fe 2 O 3 phases which have smaller size and larger surface area with slight agglomeration. Cytotoxic activities were performed on HCT‐116, HeLa and MCF‐7 cancer cell lines using MTT assay, antioxidant ability was determined using DPPH assay and bactericidal activity studies performed on Gram‐negative E coli bacteria and Gram‐positive bacteria Bacillus subtilis for the synthesized LNM Fe 2 O 3 particles which were found to be highly efficient. Biological studies revealed that synthesized luminescent nanomagnetic Fe 2 O 3 particles act as potential cytotoxic, antioxidant and bactericidal agent.