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Allergic reaction to the tetracycline component of Ledermix paste: a case report
Author(s) -
Kaufman A. Y.,
Solomonov M.,
Galieva D.,
Abbott P. V.
Publication year - 2014
Publication title -
international endodontic journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.988
H-Index - 119
eISSN - 1365-2591
pISSN - 0143-2885
DOI - 10.1111/iej.12252
Subject(s) - tetracycline , component (thermodynamics) , allergic reaction , materials science , medicine , dentistry , microbiology and biotechnology , allergy , immunology , antibiotics , physics , biology , thermodynamics
Aim Allergy to materials used during root canal treatment is well recognized in the endodontic literature. However, allergy to Ledermix paste, a compound containing triamcinolone (a corticosteroid) and demeclocycline (a tetracycline antibiotic), has not been reported apart from one very recent case in a Letter to the Editor of a journal. The aim of this report is to describe a proven allergic reaction to tetracycline following the use of Ledermix paste as a root canal medicament. Summary A 33‐year‐old female patient undergoing root canal retreatment of her right mandibular second premolar tooth experienced symptoms of type 1 allergy following the placement of an intracanal medicament containing a mixture of Ledermix paste and calcium hydroxide [Ca( OH ) 2 ]. Signs of the type 1 allergy included urticaria, pruritus all over the body, general malaise and fever. These all subsided after removing and flushing out the Ledermix paste–Ca( OH ) 2 mixture and redressing the root canal with Ca( OH ) 2 alone. Allergic scratch tests were performed, and these confirmed that the patient was allergic to tetracycline, one of the components of Ledermix paste.

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