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Efficacy of various irrigation protocols on the removal of triple antibiotic paste
Author(s) -
Arslan H.,
Capar I. D.,
Saygili G.,
Uysal B.,
Gok T.,
Ertas H.,
Topcuoglu H. S.
Publication year - 2014
Publication title -
international endodontic journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.988
H-Index - 119
eISSN - 1365-2591
pISSN - 0143-2885
DOI - 10.1111/iej.12194
Subject(s) - tap water , distilled water , root canal , sodium hypochlorite , irrigation , dentistry , stereo microscope , materials science , chemistry , medicine , chromatography , biology , environmental engineering , environmental science , agronomy , organic chemistry
Aim To compare the efficacy of irrigation protocols on the removal of triple antibiotic paste (metronidazole, ciprofloxacin and minocycline) ( TAP ) from artificial grooves in root canals. Methodology Root canals in 72 extracted single‐rooted teeth were prepared using P ro T aper rotary instruments up to size F5. The roots were split longitudinally and a standardized groove was prepared in the apical part of one segment. TAP was placed in the grooves, and the root halves were reassembled. The roots were randomly divided into six experimental groups according to the irrigation protocol used: distilled water, 1% NaOCl, 2.5% NaOCl, 100% ethanol, 17% EDTA and passive ultrasonic irrigation ( PUI ) with 1% NaOCl. The root segments were disassembled, and the amount of TAP remaining was evaluated under a stereomicroscope at 20× magnification using a four‐grade scoring system. The data were evaluated statistically using Kruskal–Wallis and Mann–Whitney U ‐tests with a 95% confidence level ( P = 0.05). Results There were significant differences amongst the groups ( P < 0.001). Passive ultrasonic irrigation ( PUI ) with 1% NaOCl removed significantly more TAP than the other irrigating solutions ( P < 0.05). Distilled water, 1% Na OC l, ethanol and EDTA were associated with significantly more remaining TAP . Conclusions PUI with 1% Na OC l was more effective in removing TAP from artificial grooves in root canals than other irrigating solutions without ultrasonic agitation. It was not possible completely to remove TAP from root canals.