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Effect of triphala mouthrinse on plaque and gingival inflammation: A systematic review and meta‐analysis of randomized controlled trials
Author(s) -
AlJameel AlBandary Hassan,
Almalki Sultan A.
Publication year - 2020
Publication title -
international journal of dental hygiene
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.674
H-Index - 38
eISSN - 1601-5037
pISSN - 1601-5029
DOI - 10.1111/idh.12444
Subject(s) - gingivitis , medicine , chlorhexidine , randomized controlled trial , gingival inflammation , dentistry , clinical trial , meta analysis , gastroenterology
Objectives To assess the efficacy of triphala mouthwash (TRP‐MW) in being equally effective to chlorhexidine mouthwash (CHX‐MW) in the treatment of plaque‐induced gingivitis. Materials and methods Electronic searches in MEDLINE/PubMed, EMBASE and CENTRAL were conducted in databases up to April 2020. Randomized clinical trials (RCTs) comparing clinical efficacy of TRP‐MW (test group) in comparison with CHX‐MW in treating plaque‐induced gingivitis were considered. The primary outcome was gingival index (GI), whereas the secondary outcome was plaque index (PI). Results Seven RCTs were included. All studies showed that TRP‐MW administration was significantly effective as compared to CHX‐MW in the treatment of plaque‐induced gingivitis. Considering the effects of TRP‐MW on clinical gingival inflammatory parameters, significant heterogeneity for both GI ( χ 2 = 72.77, P < .0001, I 2 = 91.76%) and PI ( χ 2 = 153.67, P < .0001, I 2 = 96.10%) was observed between both TRP‐MW and CHX‐MW groups. The overall mean difference for both GI (WMD = −0.29, 95% CI = −0.40 to −0.17, P < .001) and PI (WMD = −0.43, 95% CI = −0.54 to −0.31, P < .001) was statistically significant between TRP‐MW and CHX‐MW at follow‐up, respectively. Conclusion Triphala mouthwash seems to significantly improve the clinical gingival inflammatory parameters in plaque‐induced gingivitis with equal clinical efficacy as CHX‐MW. TRP is a cost‐effective alternative and is easily available with limited side effects on periodontal tissues.