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Clinical efficacy of a chlorhexidine‐based mouthrinse containing hyaluronic acid and an antidiscoloration system in patients undergoing flap surgery: A triple‐blind, parallel‐arm, randomized controlled trial
Author(s) -
Trombelli Leonardo,
Simonelli Anna,
Pramstraller Mattia,
Guarnelli Maria Elena,
Fabbri Chiara,
Maietti Elisa,
Farina Roberto
Publication year - 2018
Publication title -
international journal of dental hygiene
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.674
H-Index - 38
eISSN - 1601-5037
pISSN - 1601-5029
DOI - 10.1111/idh.12361
Subject(s) - medicine , chlorhexidine , randomized controlled trial , dentistry , wound healing , buccal administration , hyaluronic acid , tongue , periodontium , periodontal surgery , dehiscence , staining , surgery , pathology , anatomy
Objectives To evaluate the postsurgery gingival healing as well as plaque, gingival inflammation and staining levels following the use of a 0.2% chlorhexidine (CHX) solution with or without antidiscoloration system (ADS) and 0.2% hyaluronic acid (HA). Methods Patients undergoing flap surgery at sites with an intact or reduced but healthy periodontium participated in a parallel‐arm RCT. After surgery, patients used the assigned mouthrinse (CHX + HA + ADS or CHX) for 21 days. At days 7 and 21, the healing process was evaluated at experimental teeth using a composite index, namely the Gingival Healing Index (GHI). GHI score was obtained as the sum of the scores related to the severity of wound dehiscence (score 1‐3) and the profile of the buccal and oral aspects of the papilla (score 1‐3). Therefore, GHI ranged from 2 (worst quality of healing) to 6 (optimal quality of healing). Plaque Index (PlI), Gingival Index (GI), angulated bleeding score (AngBS), and tooth and tongue staining were also assessed. Results In both groups, GHI assumed values of 5 or 6 at both days 7 and 21 in ≥50% of patients, and low median values of PlI, GI, AngBS and staining were observed during the 21‐day period. Except for a significantly lower GI in CHX group at day 7, no other significant intergroup differences were found. Conclusions Postsurgery plaque control based on either CHX or CHX + HA + ADS mouthrinses results in optimal plaque control and quality of early gingival healing along with limited tooth and tongue staining.