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Clinical efficacy of desensitizing mouthwashes for the control of dentin hypersensitivity and root sensitivity: a systematic review and meta‐analysis
Author(s) -
Molina A,
GarcíaGargallo M,
Montero E,
Tobías A,
Sanz M,
Martín C
Publication year - 2017
Publication title -
international journal of dental hygiene
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.674
H-Index - 38
eISSN - 1601-5037
pISSN - 1601-5029
DOI - 10.1111/idh.12250
Subject(s) - medicine , dentin hypersensitivity , randomized controlled trial , placebo , dentistry , meta analysis , cochrane library , dentine hypersensitivity , medline , dentin , alternative medicine , pathology , political science , law
Objective This systematic review aimed to evaluate the scientific evidence on the efficacy of desensitizing mouthwashes for the treatment of dentin hypersensitivity ( DH ) and root sensitivity ( RS ). Material and methods A thorough search in MEDLINE , PubMed and Cochrane Plus Library was conducted up to February 2015. Randomized clinical trials, parallel, double‐blinded and placebo‐controlled, with a follow‐up of at least 6 weeks, reporting changes on response to tactile stimuli, thermal/evaporative stimuli or patients’ subjective assessment of the pain experienced during their daily life after the home use of desensitizing mouthwashes were considered for inclusion. Results The screening of titles and abstracts resulted in seven publications meeting the eligibility criteria. The desensitizing agents evaluated were potassium nitrate ( n = 5), aluminium lactate ( n = 1) and sodium fluoride ( n = 1). A meta‐analysis for each of the hypersensitivity stimuli was performed. Results demonstrated statistically significant reduction in sensitivity scores favouring test group when DH was assessed by means of patients’ self‐reported pain experience ( SMD at 8 weeks = 0.77; 95% CI [0.23; 1.31]; P = 0.005). No significant effects were detected in response to tactile or thermal/evaporative stimuli. Meta‐regression analysis demonstrated a tendency towards an increased effect favouring test group for the patients’ subjective perception, whereas tactile and thermal/evaporative stimuli showed a slight tendency towards a reduction in the efficacy of the test mouthwash. Conclusions There exists a tendency towards a decrease in DH or RS scores with time in both treatment groups, with significant differences in favour of test group when sensitivity is evaluated in terms of patients’ self‐reported sensitivity symptoms.