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Treatment of Periodontal Disease with an Octenidine‐based Antiseptic in HIV‐positive Patients
Author(s) -
Gušić I,
Medić D,
Radovanović Kanjuh M,
Ðurić M,
Brkić S,
Turkulov V,
Predin T,
Mirnić J
Publication year - 2016
Publication title -
international journal of dental hygiene
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.674
H-Index - 38
eISSN - 1601-5037
pISSN - 1601-5029
DOI - 10.1111/idh.12141
Subject(s) - medicine , antiseptic , periodontal disease , human immunodeficiency virus (hiv) , dentistry , antiretroviral therapy , gastroenterology , viral load , immunology , pathology
Objective To evaluate the effects of a periodontal therapy with subsequent application of an octenidine ( OCT )‐based antiseptic in HIV ‐positive patients receiving highly active antiretroviral therapy. Methods HIV ‐positive patients with a clinically diagnosed periodontal disease were randomly divided into two groups ( n = 30/group). Both groups initially received a periodontal therapy. Patients in the OCT group additionally used an OCT ‐based mouthwash. Subgingival plaque samples and periodontal indices were analysed prior to treatment onset as well as one and 3 months post‐treatment. Results Periodontal therapy has resulted in a significant decrease in the values of all periodontal indices one and 3 months following the therapy completion ( P = 0.000). The effects of the two applied therapeutic protocols differed significantly in terms of the variation in the PBI ( F = 4.617; P = 0.017) and the PD ( F = 3.203; P = 0.044) value. In the patients in the OCT group, a more pronounced decrease in the PBI and PD was noted at 1‐month follow‐up as well as a greater increase in the PD value 3 months upon treatment completion. In the OCT group, no more atypical microorganisms were detectable 1 month post‐treatment, while in the control group they were found in 34.5% of patients. Conclusions The periodontal therapy bears good results in HIV ‐positive patients. Additional administration of OCT contributes to the significant decline in the PBI and DS values and eliminates atypical microorganisms within 1 month post‐treatment. However, more favourable results were not noted in the OCT group at the 3‐month assessment.