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Comparative effect of fluoride, essential oil and chlorhexidine mouth rinses on dental plaque and gingivitis in patients with and without dental caries: a randomized controlled trial
Author(s) -
Charugundla BR,
Anjum S,
Mocherla M
Publication year - 2015
Publication title -
international journal of dental hygiene
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.674
H-Index - 38
eISSN - 1601-5037
pISSN - 1601-5029
DOI - 10.1111/idh.12094
Subject(s) - gingivitis , medicine , mouth rinse , dentistry , chlorhexidine , dental plaque , randomized controlled trial , crossover study , fluoride , oral hygiene , clinical trial , placebo , inorganic chemistry , chemistry , alternative medicine , pathology
Objectives The objective of this study was to compare the effectiveness of fluoride, essential oil ( EO ) and chlorhexidine ( CHX )‐containing mouth rinses on dental plaque and gingivitis and to compare their relative efficacy in patients with and without dental caries. Material and methods A randomized, controlled, double‐ blind, crossover clinical trial was conducted for a period of 8 weeks. Thiry‐six qualifying subjects, aged 12–44 years, were included in the study. Subjects were divided into caries and caries‐free groups and were randomly assigned to one of the following mouth rinse groups: fluoride; EO ; CHX and saline as negative control. Subjects used their respective mouth rinse for a period of 7‐days each with 1‐week wash‐out periods. Primary efficacy variables were Quigley–Hein plaque index ( PI ) and Loe and Silness gingival index. Results Fluoride and CHX mouth rinses showed significant reduction in plaque after use of mouth rinses ( P < 0.05). However, no significant differences were observed with respect to each other in reducing gingivitis ( P > 0.05). Further significant differences were found in reducing plaque and gingivitis in caries‐free subjects in comparison to those with caries ( P < 0.05). Conclusion All the three mouth rinses significantly reduced plaque accumulation and gingivitis especially in caries‐free subjects in comparison to those with caries, and amongst the three, fluoride and CHX proved to be more effective than EO mouth rinse.