Premium
The analysis of scalp irritation by coacervates produced in hair shampoo via FTIR with focal plane array detector, X‐ray photoelectron microscopy and HaCaT cells
Author(s) -
Jung I. K.,
Park S. C.,
Kim S. H.,
Kim J. H.,
Cha N. R.,
Bae W. R.,
Kim H. N.,
Cho S. A.,
Yoo J. W.,
Kim B. M.,
Lee J. H.
Publication year - 2017
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1111/ics.12360
Subject(s) - shampoo , coacervate , chemistry , pulmonary surfactant , hacat , fourier transform infrared spectroscopy , varnish , nuclear chemistry , polymer chemistry , chromatography , chemical engineering , organic chemistry , biochemistry , engineering , in vitro , coating
Objective Coacervates are inevitably formed on scalp on using hair washing products. Our goal was to analyse the coacervates in detail to identify the part responsible for scalp stimulation. Methods Shampoo that increases coacervate formation was applied to in vitro skin and was washed. The residue was then analysed using Fourier transform infrared spectroscopy–focal plane array ( FTIR ‐ FPA ) and X‐ray photoelectron microscopy ( XPS ). And HaCaT cells were used for irritant test of coacervate. Results Through this research, it was confirmed that the coacervate was a macromolecule structurally similar to a cationic polymer and contains an anionic surfactant. Its anionic surfactant was structurally semi‐stable so that it released onto scalp when it absorbs moisture. Conclusion Coacervate releases sulphate bonding into the matrix when it is exposed to water. Thus, the scalp stimulation would be expected.